How to reload php.ini after making some changes? How to reset php.ini to original state?

If you change php.ini for PHP-FPM you need to restart PHP-FPM processes with

systemctl restart php-fpm56
systemctl restart php-fpm73

systemctl reload httpd
systemctl reload nginx

Run this code

cd /usr/local/directadmin/custombuild
./build update
./build set php_ini yes
./build php-ini

Run rewrite confs to make httpd to default state.
./build rewrite_confs